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Leszek Pryszcz
Barcelona, Spain
I'm a researcher. My principal research interest lies in addressing molecular biology and evolutionary questions. I'm able to fully appreciate the complexity of biological problems because of my education in biotechnology, molecular and computational biology, as well as my extensive experience in genomic research. I’d live to develop sustainable and scalable ventures with a social impact. Founder of #NGSchool (https://ngschool.eu/).
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List your work history, including any contracts or internships
Centre for Genomic Regulation (CRG)
May 2019 - Aug 2021 (2 years 3 months)
Postdoctoral Researcher
Université de Fribourg - Universität Freiburg
Jul 2017 - Aug 2017 (1 month)
Visiting Researcher
Development of RNA editing discovery tool (https://github.com/lpryszcz/REDiscover).
RNA editing in pseudogenes.
RNA editing in pseudogenes.
Technion - Israel Institute of Technology
Nov 2016 - Dec 2016 (1 month)
Visiting Researcher
Development of HiCembler (https://github.com/lpryszcz/HiCembler/), contig scaffolder utilising HiC data.
Add some compelling projects here to demonstrate your experience
Deciphering the role of RNA editing in zebrafish development
Jan 2017 - Dec 2018
Besides extensive research and multiple proposed functions in various organisms, there is still no consensus for the purpose of RNA editing. We are studying the role of RNA editing in developing embryo. Obviously, we cannot conduct this study in human, therefore we use zebrafish (Danio rerio), as it is easy to maintain in the lab and gives access to very early developmental stages, while being relatively close to human (human share most of the genes with zebrafish).
We will characterise RNA editing in zebrafish, by sequencing parental genomes and the transcriptomes of developing embryos at several stages of development. As RNA editing is expected to create difference between transcripts and genome sequence, subsequent comparison of transcripts with genome sequence will allow genome-wide detection of RNA editing. This will allow us not only to create most comprehensive RNA editing catalogue of developing embryo, but also to identify the changes in RNA editing throughout embryo development.
This project has received funding in National Science Centre (Poland) Polonez-1 framework from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 665778.
We will characterise RNA editing in zebrafish, by sequencing parental genomes and the transcriptomes of developing embryos at several stages of development. As RNA editing is expected to create difference between transcripts and genome sequence, subsequent comparison of transcripts with genome sequence will allow genome-wide detection of RNA editing. This will allow us not only to create most comprehensive RNA editing catalogue of developing embryo, but also to identify the changes in RNA editing throughout embryo development.
This project has received funding in National Science Centre (Poland) Polonez-1 framework from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 665778.
This section lets you add any degrees or diplomas you have earned.
University Pompeu Fabra
Doctor of Philosophy (Ph.D.), Comparative Genomics
Jan 2009 - Jan 2014
Comparative genomics to unravel virulence mechanisms in fungal human pathogens
University of York
Master's degree (MRes), Computational Biology (Bioinformatics)
Jan 2008 - Jan 2009
Introductory Computing, Molecular Sequence Analysis, Introduction to Programming (Python), Structural Bioinformatics, Applied Biological Data Analysis, Simulation of Complex Biosystems, Java and Biocomputing, Introduction to Machine Learning
The University of Huddersfield
BSc (Hons), Molecular and Cellular Biology
Jan 2007 - Jan 2008
Applied Molecular Genetics, Bioinformatics, Immunology and Cancer, Molecular Medicine
Uniwersytet Śląski w Katowicach
Licentiate degree (BSc), Biotechnology
Jan 2004 - Jan 2007
Culture of Tissues and Cells, Biochemistry, Biophysics, Cellular Biology, Chemistry, Cytogenetics, Fundamental Biotechnology, Fundamental Genetics, Genetics Analysis, Genetics Engineering, Instrumental Analysis, Mathematics, Microbiology, Microscopic Image Analysis and Processing, Molecular Genetics, Quantitative Biology and many others
Planning the experiments and procedures, performing the experiment and killing the animals after procedure/experiment
Dec 2015